http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2861285-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
filingDate 2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb0925906f649e2cf429a5776bc0c25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_387f89261daf276738f71bce59810ea6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c6db7a40c548f5e20a3975d21bcbb2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d52f440bf966a5aa5f24dfb5b05f308
publicationDate 2002-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2861285-A1
titleOfInvention Decellularized tissue engineered constructs and tissues
abstract New methods for producing tissue engineered constructs and engineered native tissues are disclosed. The methods include producing a tissue engineered construct by growing cells in vitro on a substrate and then decellularizing the construct to produce a decellularized construct consisting largely of extracellular matrix components. The construct can be used immediately or stored until needed. The decellularized construct can be used for further tissue engineering, which may include seeding the construct with cells obtained from the intended recipient of the construct. During any of the growth phases required for production of the construct, the developing construct may be subjected to various tissue engineering steps such as application of mechanical stimuli including pulsatile forces. The methods also include producing an engineered native tissue by harvesting tissue from an animal or human, performing one or more tissue engineering steps on the tissue, and subjecting the tissue to decellularization. The decellularized, engineered native tissue may then be subjected to further tissue engineering steps.
priorityDate 2000-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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