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filingDate 2012-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a7f994d81777a2eaa145ff9b30aed23
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publicationDate 2013-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2861240-A1
titleOfInvention Compositions and methods of modulating an immune response
abstract Compositions for and methods of stimulating a M HC I mediated immune response comprising stimulating MHC I endolysosomal cross presentation in dendritic cells. Stimulation MHC I endolysosomal cross presentation may comprise over-expression CD74 in dendritic cells and/or targeting antigens to the MHC I endolysosomal cross presentation pathway. Fusion proteins comprising an antigen or fragment thereof and a CD74 endolysosomal targeting sequence are also provided.
priorityDate 2012-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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