abstract |
The invention relates to a process for the preparation of rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole -1-carboxamide (I) through the conversion of a 3-bromo-2-oxo-cyclohexanecarboxylic acid alkyl ester (I'-a) into 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid alkyl ester (I'-b), which in turn is processed to yield the final product (I). |