http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2848654-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79b4e51ee2130481fc3aab197ebe70c2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_643399935a27e2b5da3bbf02493ddabc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fae2f8327a3ace2c4daf2c3758072b00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b67c287f759523eebc94d58a83dbe302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b717f144b0378d2972b749669d4f10bd |
publicationDate | 2013-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2848654-A1 |
titleOfInvention | Methylation analysis on self-samples as triage tool for hpv-positive women |
abstract | The inventors now have developed a (molecular) diagnostic assay based on detection of alterations in markers MAL and hsa-mi R124, in particular promoter hypermethylation, to identify human papillomavirus (HPV)-induced high-grade precancerous lesions such as premalignant cervical lesions of invasive cervical cancer, within cell material obtained via self- sampling. In particular, the present invention relates to the use of the MAL gene (including its promoter) and the hsa-mi R124 gene as marker for HPV- induced high-grade premalignant lesions, allowing early detection and a better treatment option for the individual patient. |
priorityDate | 2011-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 323.