| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cf76b5a271319e6f17a32fbe2b9fcaf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-974
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 |
| filingDate |
2012-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe497ad3de62f13a865959e910546d6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_151a41afab7f722e53ab815b6082a564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6bbe281ccdd708e6ffc657e00d8e21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3959f3d3aa12ee7b1d97940e2e6c494c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e583be5f4f6fe032fdf10e2ee1f5745b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26ca469cb84619c20a2dfdb7ead9417c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1b9a85fac9eefa91a821ff6a541d56 |
| publicationDate |
2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2842594-A1 |
| titleOfInvention |
Method for determining the spatial and temporal distribution of the activity of a proteolytic enzyme in a heterogeneous system (variations), device for realizing same and method for diagnosing defects in the hemostatic system on the basis of a change in the spatial and temporal distribution of the activity of a proteolytic enzyme in a heterogeneous system |
| abstract |
The invention relates to the field of biotechnology. The method for determining the spatial and temporal distribution of the activity of a proteolytic enzyme in an in vitro heterogeneous system, such as blood or blood plasma, involves the introduction of a luminescent, fluorogenic or chromogenic substrate into a sample with the subsequent release of a detectable tag as the proteolytic enzyme cleaves the substrate, and the recording of the optical characteristics of the sample, which makes it possible to assess the spatial and temporal distribution of the activity of the enzyme. The device for the implementation of the above method comprises an in vitro system, a means for illuminating the sample, a recording means and a control means. A method for diagnosing homeostatic imbalances according to a change in the spatial and temporal distribution of the activity of a proteolytic enzyme in a blood sample is also proposed. |
| priorityDate |
2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |