Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f69c89ed3a6242213905509fb62e0206 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2012-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b83a2b9e1bd2eb4efcc318b7743559d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_774dadd3f262ebe4fd01cdd8e770eaa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ff3304ed7107d17ee0a605d1760339b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f406eef87ec1a97dd43781a7895dfb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d95968e55bd95eecfaa04ee0fc72093a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_062a19df71d345df345377f0821a325f |
publicationDate |
2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2834657-A1 |
titleOfInvention |
Chemical modification of apolipoprotein mimetic peptides for the production of therapeutic agents |
abstract |
Hydrocarbon stapling of apolipoprotein mimetic peptides increases the helicity of the peptides, enhances their ability to promote cholesterol efflux by multiple mechanisms and makes them resistant to proteolysis. Hydrocarbon stapled amphipathic helical peptides are useful in the treatment of cardiovascular diseases and other disorders. |
priorityDate |
2011-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |