http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2832484-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e29526f284c0155fd79806c9dd5a1c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-593 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
| filingDate | 2012-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_188f08a68e7a1a8367a4ea0b60212e32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dc39d1d78e04f552d1824d7d0d0d150 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8b2107e1cfa39dd78c18ef476afb9f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_789b85a36fd36305e7e909e38fc501eb |
| publicationDate | 2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2832484-A1 |
| titleOfInvention | Polymalic acid based nanoconjugates for imaging |
| abstract | Nanoconjugates include a polymalic-based molecular scaffold with one or more imaging moiety and one or more targeting modules attached to the scaffold. At least one imaging moiety and at least one targeting module is conjugated to the polymalicacid based molecular scaffold. Methods of synthesizing the nanoconjugate involve providing a polymalic acid having a plurality of pendant carboxyi groups. The method reacts a compound containing sulfhydryl groups and amino acid groups through the pendant carboxyi groups to add sulfhydryl groups to the polymalic acid to form an activated polymalic acid. The method reacts at least one imaging moiety containing a sulfhydryl binding group to the activated polymalic acid to form a preconjugate. The method may involve administering to the subject a nanoconjugate that includes a polymalic acid-based molecular scaffold, at least one imaging moiety, and at least one targeting module. |
| priorityDate | 2011-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.