abstract |
There are provided new dosage regimens for the gamma secretase inhibitor 2,2-Dimethyl-N- ((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide which maximizes anti-tumor activity while maintaining acceptable toxicity levels. |