abstract |
The application relates to means making it possible to determine the stage of hepatic tissue damage, in particular the hepatic fibrosis score, of subjects infected with one or more hepatitis viruses. The means of the invention implement in particular the assay of the levels of expression of selected genes, said selected genes being: - SPP1, and - at least one gene from A2M and VIM, and - at least one gene from IL8, CXCL10 and ENG, and - optionally, at least one gene from the list of the following sixteen genes: IL6ST, p14ARF, MMP9, ANGPT2, CXCL11, MMP2, MMP7, S100A4, TIMP1, CHI3L1, COL1A1, CXCL1, CXCL6, IHH, IRF9, MMP1 . |