Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7326b5c97dc18dd298e8b4e372a6f15f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 |
filingDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71f5c90b5b183db8b54487994612b333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92d7dbcd714e6934b91bc521baf66e20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_237e87ef1b9f81a1d302473d47298c60 |
publicationDate |
2011-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2802294-A1 |
titleOfInvention |
Process for n-dealkylation of tertiary amines |
abstract |
The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines. |
priorityDate |
2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |