Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4621ae6b94ebb3ab082a62a3f62e60 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57563 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
filingDate |
2011-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33da9ff57edc705fe1f106cc65749772 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69088c2d8f6b28fb81b7e00c92e50543 |
publicationDate |
2011-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2797033-A1 |
titleOfInvention |
Highly active polypeptides and methods of making and using the same |
abstract |
This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an a-amino acid and at least one ß- amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112730849-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112730849-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114113639-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114380889-A |
priorityDate |
2010-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |