http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2789373-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad68395cc506624ac5501658a6644489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B43-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B37-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-64 |
| filingDate | 2011-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62af7a42f496a2f7f1e58e8fcb8e86dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fb955c9ac928d3a19def499dc0c82d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0db1579ccb3893b9db25c2c4b6ef5ec0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e223cee6ac2113c6bf801725a4c74f8 |
| publicationDate | 2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2789373-A1 |
| titleOfInvention | Process for preparing chemical compounds of interest by nucleophilic aromatic substitution of aromatic carboxylic acid derivatives supporting at least one electro-attractive group |
| abstract | The present invention relates to a method for preparing aromatic carboxylic acid derivatives by nucleophilic aromatic substitution, which involves reacting an aromatic carboxylic acid derivative supporting only one carboxyl function, or one of the salts thereof, said carboxylic acid derivative supporting, orthogonally to the carboxyl function, a splitting group which is an atom of fluorine or chlorine or an alcoxy group, chiral or otherwise and, in the latter case, a methoxy group is preferred; said carboxylic acid derivative being substituted by at least one electro-attractive group other than the splitting group, preferably by a fluorine atom, with a MNu reagent, wherein M is a metal and Nu is an optionally chiral nucleophile, said nucleophilic aromatic substitution reaction being carried out without a catalyst and without a step of protecting/unprotecting the acid function of the initial compound, said method being selective in that the reaction leads to the formation of ketone derivatives in a very minority fashion during the reaction. |
| priorityDate | 2010-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.