| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b28ce248ecea72afa9016c761d164369 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-78 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-22 |
| filingDate |
2011-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21192283f15fdc5da7e120783251f0cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fb4fa369d5f1491481b921dc69ee621
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fb022a8aafec5547ea74265cd7b0f30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d7799065878cfe1ef40397558e8fff2 |
| publicationDate |
2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2789344-A1 |
| titleOfInvention |
Synthesis of bicyclic compounds and method for their use as therapeutic agents |
| abstract |
Disclosed embodiments concern the synthesis and use of therapeutic compounds that for treating emerging flu strains and minimizing resistance to such strains. Methods for making the disclosed compounds concern using a base-mediated addition/cyclization sequence followed by functional group manipulation to develop functionalized compounds that can target neuraminidase, which makes them ideal candidates for treating influenza. Pharmaceutical compositions comprising the therapeutic compounds and biologically-acceptable materials are also described. Methods of inhibiting neuraminidase in subjects that are suspected of containing neuraminidase are also described. The use of metabolites of the disclosed compounds can also be used in diagnostic assays for therapeutic dosing of the disclosed compounds. |
| priorityDate |
2010-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |