http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2786646-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cac023d2e2874224ecbbcccbdea1fc91 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-10 |
| filingDate | 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac6d4c3168ed1a7b082f088e878992e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e275f8af89345cec17f0c9a70a2c3bff |
| publicationDate | 2011-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2786646-A1 |
| titleOfInvention | Method for producing 3,4-disubstituted pyrrolidine derivative and production intermediate thereof |
| abstract | Disclosed is an economical and industrially advantageous method for producing a (3R,4S)-3-(N-substituted-aminomethyl)-4-fluoropyrrolidine, which is usable as an intermediate in producing a medicine, or an enantiomer thereof. Specifically disclosed is a method for producing a (3R,4S)-3-(N-substituted-cyclopropylaminomethyl)-4-fluoropyrrolidine derivative, an enantiomer thereof or a salt of the same, comprising a step for fluorinating a 4-hydroxy-3-(N-substituted-aminomethyl)pyrrolidine derivative represented by general formula (1) or an enantiomer thereof by using a sulfur tetrafluoride derivative. In general formula (1), PG represents a protecting group for the amino group; and R1 represents an optionally substituted C1-6 alkyl group or an optionally substituted C3-8 cycloalkyl group. |
| priorityDate | 2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.