abstract |
A cyclic organic compound which comprises 16 amino acids or 17 amino acids and has no carboxyl group C-terminally and/or no amino group N-terminally, wherein, optionally, one of the amino acids is a nonnatural amino acid, and wherein the ring closure is formed between a side chain of one amino acid and the C-terminus of another amino acid, or the ring closure is effected with the aid of a nonnatural amino acid, a process for its production and its use for the regulation of vectorial ion channels, for the treatment of diseases associated with the lung function and for the treatment of oedemas. |