http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2780827-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57f3e2af72b2933c004ed61dfccaaee1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a148a028a0f40c0b195e3a57eba8687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f84b175b41af025a390afc09c3ebb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d305e4a24bf4a11dbf7b4687c46fb7ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52e307808647801d15a5ad657ab72a95 |
| publicationDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2780827-A1 |
| titleOfInvention | Methods for producing uniquely specific nucleic acid probes |
| abstract | Disclosed herein are uniquely specific nucleic acid probes and methods for their use and production. The disclosed probes have reduced or eliminated background signal while reducing or eliminating the use of blocking DNA during hybridization. In one example, probes are produced by a method that includes joining at least a first binding region and a second binding region in a predetermined order and orientation, wherein the first binding region and second binding region are complementary to uniquely specific nucleic acid sequences, wherein the uniquely specific nucleic acid sequences are represented only once in a genome of an organism and wherein the first binding region and the second binding region include about 20% or less of a genomic target nucleic acid molecule. In particular examples, the binding regions ("uniquely specific binding regions") are complementary to non-contiguous portions of the genomic target nucleic acid. Methods of using the disclosed probes and kits including the probes and/or reagents for producing or using the probes are also disclosed. |
| priorityDate | 2009-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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