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filingDate 2010-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2779386-C
titleOfInvention Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation
abstract Apparatus and methods for deactivating renal nerves extending along a renal artery of a mammalian subject to treat hypertension and related conditions. An ultrasonic transducer (30) is inserted into the renal artery (10) as, for example, by advancing the distal end of a catheter (18) bearing the transducer into the renal artery. The ultrasonic transducer emits unfocused ultrasound so as to heat tissues throughout a relatively large impact volume (11) as, for example, at least about 0.5 cm3 encompassing the renal artery to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual renal nerves.
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