http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2770680-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_125f9fd20b43e12df366a0289f2124e8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70535 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 |
| filingDate | 2010-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c307f0b693033bf802831848d15fd434 |
| publicationDate | 2011-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2770680-A1 |
| titleOfInvention | Methods of detecting responses to therapies using perforin levels |
| abstract | Methods and kits for detecting positive responses to therapies, diagnosing a disease or condition, and detecting impending clinical relapse. The method may feature obtaining a sample from a patient and either detecting a percentage of perforin+ natural killer (NK) cells or detecting a level of perforin expression in the sample. Positive responses to the therapy may be detected if the percentage of perforins NK ceils is greater than or equal to about 75% of total NK ceils or if the level of perforin expression in the sample is within a ievel of perforin expression in a normal sample +/-25%. The disease or condition or impending clinical relapse may be detected if the ievel of perforin expression in the sample is less than a level of perforin expression in a normal sample minus about 25% or the percentage of perforin+ NK ceils is less than about 75% of total NK cells. |
| priorityDate | 2009-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.