http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2764490-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3155069b833b184bcd4ad12f7100dd4c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate | 2010-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_484fbbbfdaa6717ddc2aa28d8cd1409b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_247c926d27b43a5d8a1a1118fce44e91 |
publicationDate | 2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2764490-A1 |
titleOfInvention | Antimicrobial peptides |
abstract | Disclosed are antimicrobial peptides with desirable levels of hemolysis, and advantageous therapeutic index against various microorganisms, especially P. aeruginosa, A baumannii and S. aureus. Also provided are methods of controlling microbial growth and pharmaceutical compositions to treat or prevent microbial infections. Certain peptides are modified with single D-/L- amino acid substitutions or charged residue substitutions in or near the center of the peptide on the nonpolar or polar face, or peptides with one or more amino acids in the D configuration, for improved activity or resistance to degradation. |
priorityDate | 2009-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 138.