http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2763321-C

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57f3e2af72b2933c004ed61dfccaaee1
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-10
filingDate 2010-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b53834d4f4a0366b5036ed7e37d24d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df4089308afc4224ba367dcdf02e8581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290f4a7973bed36ffe411e53731de205
publicationDate 2018-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2763321-C
titleOfInvention Methods of scoring gene copy number in a biological sample using in situ hybridization
abstract Disclosed herein are methods of predicting prognosis of a neoplastic disease (such as lung cancer, for example NSCLC), including determining the IGF1R gene copy number in a biological sample from a patient having a neoplastic disease; wherein an increase in IGF1R copy number predicts a good prognosis of the neoplastic disease in the patient. Also disclosed herein are methods of scoring copy number of a gene of interest in a biological sample. The method includes identifying individual cells in the sample having highest number of signals for the gene of interest detected by in situ hybridization, counting the number of signals for the gene of interest in the identified individual cells and determining an average number of signals per cell.
priorityDate 2009-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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