http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2761471-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2b25cf8265f5391a0e721a91c17826e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-50 |
| filingDate | 2010-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc540860a02d733e0f3b79dca3e2acde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cfe3d495ab019322fc10df4be15fbcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb6d6b8be69bd00c9c554de92d7f234c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f17476c9586fbf9bbb62e38bf1d8ca |
| publicationDate | 2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2761471-C |
| titleOfInvention | Biologically produced cyclic affinity tags. |
| abstract | The invention relates to novels ways of introducing an affinity tag into a protein of interest. Provided is an enzy-matic method for providing a proteinaceous substance comprising a polypeptide of interest and a cyclic affinity tag, comprising the steps of: (a) providing at least one precursor proteinaceous substance, the precursor comprising said protein of interest and at least one motif of the general formula X1-Tag-X2, wherein X1 and X2 represent amino acids whose side chains can be linked enzymatically by a covalent bond; Tag is a short amino acid sequence capable of binding to a binding partner of the tag when cy-clized; (b) contacting said precursor with at least one enzyme capable of forming a covalent bond between X1 and X2, thereby in-troducing an intramolecular ring structure comprising the Tag sequence; and (c) isolating the resulting cyclized proteinaceous substance. Also provided are proteinaceous substances obtainable thereby and the use thereof, for instance for preparing a peptide li-brary. |
| priorityDate | 2009-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.