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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12622c5504b328fa3843e22c6f4b3f01
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54
filingDate 2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d64dad6b277215d9737e8acf778cedf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aaf7fc48e6cbd70381ef9a0f5c5074b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0396baa12d17df44975c3adeb2d466a1
publicationDate 2010-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2759695-A1
titleOfInvention Proteases with modified pro regions
abstract The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. Bacillus sp. host cells. The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
priorityDate 2009-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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