| abstract |
The present invention relates to methods of deter-mining intracellular Cbl-b protein in cells of a sample, comprising .cndot. introducing an antibody, which binds Cbl-b intra-cellularly, into a cell, .cndot. allowing contracting of the antibody and Cbl-b protein potentially present in the cell, .cndot. detecting binding events between the antibody and Cbl-b, .cndot. quantifying the detected binding events, whereby the content of Cbl-b protein is determined. |