http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2758019-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2174dd7ac8f6855b2b6a2019d2e222ad |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2010-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6351068ec8fee74fc7a5efc03fcd399 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f94a7ec89c987947338f93370c1c52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f4b7cb114dfc1f80f320c4775fb0a02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_625983eed7823ef658cf02a9e9d49bb8 |
| publicationDate | 2010-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2758019-A1 |
| titleOfInvention | Imidaz0[1,2-a] pyridine-6-carboxamide derivatives, their use for the treatment of colon cancer and their method of manufacture |
| abstract | This invention relates to the manufacture of novel chemical compounds which have biological activity, particularly to novel chemical compounds that are cytotoxic against colon cancer cells and colon cancer cell lines. The manufacturing of said chemical compounds displaying anti-cancer properties employs the use of multi-component chemical reactions. The object of this invention is to manufacture and isolate analogues of imidazo[1,2-a]pyridine, namely compounds of Formula 1, which are cytotoxic against colon cancer cells, while concomitantly being relatively inactive against white blood cells. Formula 1 wherein, R is bromo, methyl, phenyl, nitro, hydrogen or an amide functional group; R1 is benzyl, 2,6-dimethylphenyl or cyclohexyl; and R2 is methoxy, benzyloxy or hydroxy. |
| priorityDate | 2009-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.