http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2751741-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-80 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-80 |
filingDate | 2009-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3e69925be61fd82aaf05b7e655ccfe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abeb6eb9a3afc03b7093b2ff839efe34 |
publicationDate | 2009-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2751741-A1 |
titleOfInvention | Process for the preparation of (-) -delta 9-tetrahydrocannabinol |
abstract | The present disclosure is directed to a process for the chemical syn-thesis of (-)-.DELTA.9- ^tetrahydrocannabinol (.DELTA.9--THC) and related compounds of formula (I). In particular, the process comprises a one-pot condensation and sulfonylatton re-action sequence that produces crude .DELTA.9--THC aryl sulfonate or related compounds. Sulfo.pi.ylatio.pi. of .DELTA.9-THC or related com-pounds immediately upon their formation imparts stability to the cannabinoids, and prevents formation of the corresponding .DELTA.8 isomer. .DELTA.9THC aryl sulfonates may be readily separated from A6THC aryl sul-fonates using reverse phase chromatogra-phy. Hydrolysis of the .DELTA.9-THC aryl sul-fonates or related compounds produces .DELTA.9--THC or related compounds containing rel-atively low amounts of the corresponding .DELTA.8 isomer. (Formula I). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11084770-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11202771-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11040932-B2 |
priorityDate | 2008-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.