| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44 |
| filingDate |
2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5636df2eb998a36e7b59911ce6090856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d39aec2403ff8fb8894106fc038a34d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42456709e19d738197b8a09da7d456ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e0c1fbe64658cb5ea16e156e2ec9c0b |
| publicationDate |
2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2748758-A1 |
| titleOfInvention |
Antibodies against phosphorylated tyrosines on erythropoietin receptor (epor) |
| abstract |
An isolated antibody binding to human EPO receptor. The antibody specifically binds EPO receptor fragment GLSDGPYSNPYENSLIP (SEQ ID NO:26), comprises a phospho-tyrosyl residue at position 465, and specifically binds to activated human EPO receptor and discriminates between non activated and activated EPO-R. The heavy chain variable domain comprises a CDR3 region of SEQ ID NO:17, a CDR2 region of SEQ ID NO:18 and a CDR1 region of SEQ ID NO:19, and the light chain variable domain comprises a CDR3 region of SEQ ID NO: 20, a CDR2 region of SEQ ID NO:21 and a CDR1 region of SEQ ID NO:22. The antibody specifically binds pY465 in ELISA at a S/N ratio of 10 or more at an antibody concentration of 0.1µg/m1. |
| priorityDate |
2009-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |