http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2740311-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7eaa81e19711e1e1ee4ab27501c4ea0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b7f9c6339142ba160abfe36a625820 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6382decde11d5ca2c336336e589aed08 |
| publicationDate | 2013-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2740311-C |
| titleOfInvention | Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides |
| abstract | The present invention provides novel methods for preparing 5-(trifluoromethoxy)-1H-3- indazolecarboxylic acid (3), which is a useful precursor for the preparation of bicyclic-5-trifluoromethoxy-1H-indazole-S-carboxylic acid amides of Formula (1). Compounds of Formula (1) are active as agonists and partial agonists of the nicotinic .alpha.-7 receptor and are being studied for their use in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders. The present methods are useful for preparing compound (3) on scale up levels. |
| priorityDate | 2008-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.