http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2736163-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c524179979207d2c854b061e857d0c4d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D411-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D411-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-048 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
filingDate | 2008-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16448a5b0312310cc51475e562149148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68a2f2d1f43b1f048fc14dc887d32642 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec76c62cd30de47b6f6a7f163671b592 |
publicationDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2736163-C |
titleOfInvention | Enantiomeric resolution of 2,4-disubstituted 1,3-oxathiolane nucleosides |
abstract | Single enantionmers of compounds of formula (B), in either the cis or trans configuration, (B) wherein R1 and R2 are as defined herein, can be separated from enantiomeric mixtures thereof by reacting the compound with an acid to produce a conglomerate salt that has the following characteristics: the IR spectrum of the salt of the racemic compound, a 1:1 mixture of (-) and (+) crystals, is identical to that of the each of the single enantiomer, and the salt of the racemic compound has a melting point lower that that of either single enantiomer. The conglomerate salt is then separated by preferential crystallization. |
priorityDate | 2008-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.