Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fad53c9da69abd8e97bef3936627147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aea57db10fe6e572d4a54808447081e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b3e6d16e5e895914f023d28f1d137ab |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2009-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07f2fff52d7271d4e6dde38d5e49c3ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90a49336ece2d330a1ef497165c49705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376ca014a0057ed02f1cfbd406a05abc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b176dc40c08b2091a4d4d3ea61a61d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a62d5ab5f428ada5dd8e316f549d60 |
publicationDate |
2009-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2729000-A1 |
titleOfInvention |
Blood transcriptional signature of mycobacterium tuberculosis infection |
abstract |
The present invention includes methods, systems and kits for distinguishing between active and latent mycobacterium tuberculosis infection in a patient suspected of being infected with mycobacterium tuberculosis, and distinguishing such patients from uninfected individuals, the method including the steps of obtaining a gene expression dataset from a whole blood obtained sample from the patient and determining the differential expression of one or more transcriptional gene expression modules that distinguish between infected and non-infected patients, wherein the dataset demonstrates an aggregate change in the levels of polynucleotides in the one or more transcriptional gene expression modules as compared to matched non- infected patients, thereby distinguishing between active and latent mycobacterium tuberculosis infection. |
priorityDate |
2008-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |