http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2727792-C

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14
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filingDate 2008-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d63d8c55f02f2514c438a031b5e89c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef5e2380ffe1be2ead64458531a8bb8
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publicationDate 2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2727792-C
titleOfInvention Antitumoral terpenoid pharmaceutical composition abisilin exhibiting angiogenesis-inhibiting action
abstract The invention relates to medicine and the chemical and pharmaceutical industry and to agents for treating diseases caused by angiogenesis regulation disorders, in particular to a method for treating oncological diseases of different genesis by inducing angiogenesis inhibition which is secondary to the direct antitumoral, anti-reccurant and anti-metastatic action as well as by the associated activation of the apoptosis endogenous system. The invention uses a novel peroral medicinal form 'Abisilin', comprising ingredients relating to the class of natural terpene compounds (isoprenoids), produced from coniferous threes of a Pinaceae family, which medicinal form contains: sesquiterpenoids (3-6%), neutral diterpenoids (11-15%), diterpene acids (22-28%), triterpene acids (8-16%), unsaturated and saturated fatty acids (0.1-0.3%), phenolic compounds (0.1-0.2%), monoterpenoids being the rest, wherein the bornyl acetate content is equal to not less that 10.0% of the total terpene composition. It is expected that the use of the novel peroral medicinal form 'Abisilin', the substance of which exhibits immunomodulating, antibacterial, antiinflammatory, anesthetic, wound-healing and other pharmacologically-significant actions, is free of contra-indications and toxic effects and can be used together with different agents, provides a novel therapeutic approach and enhances the efficiency of treatment of oncological and many other diseases caused by angiogenesis process disorders.
priorityDate 2008-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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