| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea803fedb641d0973cb43b9fbea9840f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
2009-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e12b52ca88141908f4d28b7caec21fc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ca55d0d2a3214663971b0e3e80ad520
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9ee14459309a18becf1f44122d51456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79858df341fc97ace6612f1bd7e235a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4daabaaf1c66a8498d72157862b132a0 |
| publicationDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2724525-A1 |
| titleOfInvention |
Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof |
| abstract |
In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding por-tion of the extracellular domain of activin-like kinase I (ALK1) polypeptide may be used to inhibit angiogenesis in vivo, particu-larly in mammals suffering angiogenesis-related disorders. In certain aspects, the disclosure demonstrates that antagonists of BMP9 and/or BMP10, ligands for ALK1, may also be used to inhibit angiogenesis in vivo. |
| priorityDate |
2008-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |