Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2872 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2008-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16eb5e4ea4ca9d6f3ba3cc8f8da738e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5af81c8628defdc95f0ba4861a8947d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17fa6820111da0df384a29507c425062 |
publicationDate |
2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2719878-A1 |
titleOfInvention |
Prion protein as a receptor for amyloid-beta oligomers |
abstract |
The invention provides methods of inhbiting suppression of long term potentiation, improving acute memory re-tention and spatial memory performance and treating Alzheimer's disease by administration of a PrPc antagonist or combinations thereof. Additionally, this invention provides pharmaceutical kits comprising, and methods for making and using, such combinit-tions, as well as methods of identifying molecules that could function as PrP c antagonists. |
priorityDate |
2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |