| abstract |
The present invention re-lates to compounds of formula (I) where-in R1, R2, R4, R5, R a, R b, n, W and Z are as defined in the application, their prepa-ration and their use as P2Y12 receptor antagonists in the treatment and/or pre-vention of peripheral vascular, of viscer-al-, hepatic- and renal-vascular, of car-diovascular and of cerebrovascular dis-eases or conditions associated with platelet aggregation, including thrombo-sis in humans and other mammals. |