Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12622c5504b328fa3843e22c6f4b3f01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y108-01009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y108-01008 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate |
2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51d1a83d812e6b902bf3373731d48b75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45ed68ddf1599149c9d16d2dd56ed8fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baba3e5178eb0438007ea7328ce1f9fb |
publicationDate |
2009-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2719559-A1 |
titleOfInvention |
Host cells and methods of producing disulfide bond containing proteins |
abstract |
The invention provides for genetically modified Bacillus host cells having decreased cytoplasmic reductase activity, such as decreased TrxA activity, and a nucleic acid encoding a heterologous Staphylococcal oxidase. The invention also provides for methods of producing di-sulfide bond containing proteins using the host cells of the invention and methods of improving protein folding using the host cell of the invention. |
priorityDate |
2008-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |