| abstract |
The invention relates to novel products of formula (I) in which Het represents an optionally substituted heterocycle by one or more radicals R1 or R'1, R is chosen from the group consisting of by (A '), (B), (C), (D) and (E) with R1 and / or R'1, selected from H, halogen, CF3, nitro, cyano, alkyl, hydroxy, mercapto, amino, alkylamino, dialkylamino, alkoxy, phenylalkoxy, alkylthio, carboxy free or esterified with an alkyl radical, carboxamide, CO-NH (alkyl), CON (alkyl) 2, NH-CO-alkyl, sulfonamide, NH-SO2-alkyl, S (O) 2-NHalkyl, S (O2) -N (alkyl) 2; all these radicals eventually substituted; W1, W2, W3 represent independently CH or N, X is O, S, NR 2, C (O), S (O) or S (O) 2; Z represents H, Hal, -O-R2 or -NH-R2 with R2 represents H, alkyl, cycloalkyl or optionally heterocycloalkyl substituted; these products being in all forms isomers and salts as medicaments. |