| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e41db90b05654c0207bd44faaef1b04 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8257
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate |
2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a6e8fb44b7cc5afa332deb6f534b816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b30887f0dfcb04e40a54c6bd625ede3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d325f2cd7a388bd06be3ac5d061b4867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2253732a83ba935d3b3b4e5b0ab7dbd |
| publicationDate |
2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2717543-A1 |
| titleOfInvention |
A method for the production of a human protein in a plant, in particular a human recombinant lysosomal enzyme in a cereal endosperm |
| abstract |
A method for the production of a human protein in plant, in particular of a human recombinant lysosomal enzyme in a plant endosperm, comprising: - a first step of plant transformation whereby the protein is obtained and confined in an endosperm, which is not eventually absorbed by the embryo, and the presence of large quantities of the protein in the endosperm does not negatively affect seed viability and germination speed; - the use, in the first step of plant transformation, of an endosperm-specific promoter upstream the gene encoding said protein, and of a signal peptide for a co-translational transfer of the newly synthesized protein into the lumen of the endoplasmic reticulum of the endosperm cells for its tissue-specific accumulation; - a second step of protein accumulation inside the seed endosperm of a plant. |
| priorityDate |
2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |