http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2715728-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eb84eabb33a184477bc90767646d589 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5395 |
| filingDate | 2009-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2caf9762278636aeb6e9d3afd6f969aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c4fb883b7a286fdfee726b32a7595e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e97219d211572fd3e1b4c72a36a12c3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95309c223f6732ee180ee3b3ea65a7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b863285014291cc0cc2a8310762e1517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda285070a740579297878e2ba42430a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dca005276cd1f28308321693ac1573f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d406615136127aca2d273546a221f35 |
| publicationDate | 2009-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2715728-A1 |
| titleOfInvention | Novel 7-substituted derivatives of 3-carboxy-oxadiazino-quinolone, prep aration thereof and use thereof as anti-bacterials |
| abstract | A subject of the invention is the compounds of formula (I): in which - either R1 represents H, OH, NH2,-(CH2)m - NR a R b (m = 0.1 or 2), R a and R b represent H, linear, branched or cyclic (C1-C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)-alkyl, R c, S(O)2R c, C(O)R c, S(O)2R d or C(O)R d; or R a and R b with N form an R c radical; R c represents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted; R d represents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens; or R1 represents R, or CHR e R c or CHR e R d, R e represents H, OH, NH2, NH-(C1-C6)-alk or N-(C1-C6)-alk2, or NH-(C1-C7)-acyl or NHR c; R2 represents H, (CH2)m NR a R b, R, CHR e R c or CHR e R d, and R'2 represents H; it being understood that R1 and R2 cannot at the same time be H or that R1 and R2 or R2 and R1 cannot be one (CH2)m NR a R b or & or H and the other one OH, or one H and the other one NH2, or one H and the other one (CH2)m NR a R b in which R a and R b represent H or alkyl or C(O)R d, in which R d represents an unsubstituted alkyl or cycloalkyl; - or R1 has the above definition except H and R2 and R'2 together represent gem dialkyl or alkyl-oxime, or R2 and R'2 represent respectively R c or R d and OH, NH2, NHR c or NHR f, R f being a(C1-C7) acyl radical; - or R1 represents H and R2 and R'2 together represent alkyl-oxime or one represents R c and the other one represents OH, NH2, NHR, or NHR f; n is 0 or 1; R3 and R'3 represent H or (C1-C6) alkyl optionally substituted by 1 to 3 halogens or R3 represents (C1-C6) alkoxy carbonyl and R'3 represents H; R4 represents methyl optionally substituted by halogen; R5 represents H, (C1-C6) alkyl or (C7-C12) arylalkyl; R6 represents H, fluorine, NO2, CF3 or CN; in the form of enantiomers or niixtures, as well as their salts with acids and bases; their preparation and their application as anti-bacterials, in both human and veterinary medicine. |
| priorityDate | 2008-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 268.