| abstract |
independently of one another, a nitrogen atom or a group C-R1; W represents an oxygen or sulfur atom; n is equal to 0, 1, 2 or 3; Y is an optionally substituted aryl or heteroaryl substituted; A represents the group of formula: (II) Z1, Z2, Z3 and Z4 represent, independently of one another, a nitrogen atom, or a group C-R2; Ra and Rb form together with the carbon atoms that carry them, ie a partially unsaturated cycloalkyl, an aryl; either a heterocycle or a heteroaryl 5- to 7-membered group comprising from one to three heteroatoms selected from O, S or NOT; this cycloalkyl, this aryl, this heterocycle or this heteroaryl may be substituted with one or more substituents R3; at the basic state or salt of addition to an acid, as well as the state of hydrate or solvate. Preparation process and application in therapeutic. |