http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2705848-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0eedf57f4a4e487d7872cb14f7b3c925 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate | 2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39b3b3a81ac06eb23d9101d3f0ac6fc6 |
| publicationDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2705848-C |
| titleOfInvention | Photoluminescent metal complexes for protein staining |
| abstract | A method of staining a poly(amino acid) by contacting a poly(amino acid) with a complex of at least one of transition metal ion, and a plurality of donor ligands each of which is fully coordinated to the transition metal ion and is either a nitrogen donor ligand or a cyclometalated donor ligand, such that at least one of the donor ligands is a cyclometalated donor ligand. Donor ligands in a single complex can be the same or different. Nitrogen donor ligands will contain heteroaryl ring systems having from 10 to 40 ring atoms, where from 2 to 8 ring atoms are N, O, S, or combinations thereof, such that at least two ring atoms are N, wherein each nitrogen donor ligand is substituted with from 0 to 4 R1 groups. Cyclometalated donor ligands will likewise contain heteroaryl ring systems having from 10 to 40 ring atoms, where from 1 to 4 ring atoms are N, O, S or combinations thereof, such that at least one ring atom is N, wherein each Cyclometalated donor ligand is substituted with from 0 to 4 R1 groups. The R1 groups are C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C-6 alkoxy, halogen, C1-6 haloalkyl, OR2, NR2R3, CN, C(O)R2, C(O)OR2, OC(O)R2, C(O)NR2R3, N(R2)C(O)R3, OC(O)NR2R3 N(R2)C(O)OR3)C(O)OR3, NR2C(O)NR3R4, NR2C(S)NR3R4, NO2, =O, aryl, heteroaryl, cycloalkyl or heterocycloalkyl. When two or more R1 groups are present on a single donor ligand, they can be the same or different. The R2, R3 and R4 groups are H or C1-12 alkyl. Each of the R2, R3 and R4 groups can be the same or different. Furthermore, the metal complex of the present invention is neutral or cationic in overall electronic charge, such that the metal complex is non covalently associated with the poly(amino acid). Thus, the metal complex stains the poly(amino acid). |
| priorityDate | 2007-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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