abstract |
The present invention relates to 7-azaindole derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1(11.beta.-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteo-porosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions. |