http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2703365-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78d4470ccfa7e1f4fd24a95c2f852ae3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30b9e46e74783477ee86f7f22dbb84c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b94da377f1c117deef08432af9fff4 |
| publicationDate | 2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2703365-A1 |
| titleOfInvention | Nifedipine-containing press coated tablet and method of preparing the same |
| abstract | A sustained release nifedipine-containing press coated tablet, which comprises (A) a core comprising nifedipine and a hydrophilic gel-forming high molecular substance, wherein the dissolution of the nifedipine from the core is designed to be delayed: and (B) an outer shell coating said core, which comprises (i) (a) nifedipine and (b) a disintegration suppression substance comprising a pH-independent water-insoluble polymer, wherein the combined contents of (a) and (b) are in the range of 8 to 22 % by weight based on the total weight of the outer shell, and (ii) a hydrophilic gel-forming high molecular substance selected from cellulose derivatives and polyvinyl alcohols, wherein the content thereof is in the range of 76 to 95 % by weight based on the total weight of the outer shell, which is characterized in that the diameter of said tablet is 7.5 to 8.5 mm, and the thickness thereof is 4.5 to 5.2 mm, and further characterized in that the dissolution rate of nifedipine from said tablet is controlled within a specific range. The tablet of the present invention is miniaturized as compared to the currently-used nifedipine-containing tablets but the dissolution properties and bioavailability of nifedipine therein are not changed. |
| priorityDate | 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.