Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0867 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 |
filingDate |
2008-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d165fa48934c81ecf0c289204d759ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c6f94ec034951cb2ef0bea440751a7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48dfddf1fbc8aeed6394919757694e0b |
publicationDate |
2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2694545-C |
titleOfInvention |
Arrays comprising a plurality of wells, each well releasably attached to a patterned plurality of different antibodies |
abstract |
The disclosure provides an array for the multiplexed analysis of a plurality of biomolecules, wherein each well provides a distinct signature of at least one cell or its cellular components. Exemplary arrays comprise a solid substrate comprising a surface and a plurality of primary antibodies attached thereto in a pattern. The plurality of primary antibodies bind different cellular components. Between 3 and 50 different primary antibodies are attached to the solid surface in the pattern. When a polydimethylsiloxane mold comprising a plurality of wells is releasably coupled with the solid substrate, the plurality of wells are oriented to intersect with the pattern of attached primary antibodies and each well is exposed to the pattern of attached primary antibodies. The selective binding of each primary antibody and its target biomolecule is labeled by a detectable secondary antibody. The resultant pattern of detectable secondary antibodies comprises the distinct signature of each well. |
priorityDate |
2007-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |