Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4f16ad70ddfeb0b838c113aaae408a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-84 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-42 |
filingDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e80107e622dc5b02541d1931f76e81b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5135fad9fd7caaa06d42f33c1b827e7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f298c66882cff926861cd940ead4a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae913d1fe3e4f1d66f0e8401fe017726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e281536d0b4fc5374dfb2d4e10ab0d3 |
publicationDate |
2007-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2694439-A1 |
titleOfInvention |
Novel processes for preparing sertraline hydrochloride crystalline forms |
abstract |
The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25 - 30°C, pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25 - 30°C and then stirred for 14 hours at 25 - 30°C. Filtered the solid and dried at 65°C for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I. |
priorityDate |
2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |