| abstract |
The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyr.tau.oIidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyr.pi.>lidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIb) Where U is independently selected from: (I) or (II) |