http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2686645-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D225-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-08 |
| filingDate | 2008-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f46806c2aeb627c2277402f42339388 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209259f9f93ce12923b6dae8f91c4a70 |
| publicationDate | 2015-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2686645-C |
| titleOfInvention | Process for the preparation of dibenzo [b,d]azepin-6-one derivative |
| abstract | The invention relates to a process for the optical resolution of a dibenzo[b,d]azepinone derivative of the formula (II) wherein R1 is hydrogen or halogen and R2 has the meaning of C1- 4-alkyl optionally substituted with C3-7-cycloalkyl or benzyl which is optionally substituted with C1-4-alkoxy to obtain a (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one of the formula (I) wherein R1 is as above. The (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-ones of formula (I) can be used as chiral building blocks for the preparation of malonamide derivatives which have the potential to act as .gamma.-secretase inhibitors and therefore may be useful in the treatment of Alzheimer's disease and cancer. |
| priorityDate | 2007-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.