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filingDate 2008-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac7fc7d0a9524146822c1a5919296f4b
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publicationDate 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2683023-C
titleOfInvention Mr methods of grading a tumor using an imaging medium that comprises hyperpolarized 13c-pyruvate
abstract The application relates to MR methods of grading a tumor using an imaging medium which comprises hyperpolarized 13C-pyruvate. In particular, it relates to a method of determining the grade of a tumor, said method comprises a) MR detecting a tumor in a subject using an imaging medium that comprises hyperpolarized13C-pyruvate wherein signals of 13C-pyruvate and its 13C-containing metabolites alanine, lactate and optionally bicarbonate are detected; b) using said signals and optionally the total carbon signal to generate a metabolic profile of the tumor; c) comparing the metabolic profile of the tumor generated in step b) to a known metabolic profile of a tumor of a certain grade; and d) determining the grade of the tumor based on the similarities and differences between said metabolic profile of the tumor and said known metabolic profile.
priorityDate 2007-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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