http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2680528-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5edde3db28268dc748d2dab8e10ab06 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-00 |
| filingDate | 2008-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1244a8ff7a745c0a1115b3ebe93cee47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89bf6b0f9e8b54a6d2b65f57b215897f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1fb38631864963f26660e8ddc52c7ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e519e238811e68b6eace6a65a2977fb0 |
| publicationDate | 2008-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2680528-A1 |
| titleOfInvention | Methods for evaluating angiogenic potential in culture |
| abstract | The present invention provides a method of evaluating the angiogenic potential of a tumor, and for predicting the efficacy of anti-angiogenic therapies on an individualized basis. The method of the invention involves preparing an angiogenic signature for malignant cells in culture by assaying for the presence or level of one or more angiogenesis-related factors selected from VEGF/VPF, IL8/CXCL8, TGF-.beta.1, TGF-.beta.2, TGF-.beta.3, bFGF/FGF-2, EGF, PDGF-AA, PDGF-AA/BB, IP-10, and Flt-3 ligand. The angiogenic signature may be prepared from cultures maintained under normoxic and/or hypoxic environments. The invention may be used in conjunction with chemoresponse testing of anti-tumor agents, to predict or suggest a combination therapy for cancer patients. |
| priorityDate | 2007-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 618.