abstract |
The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocyclyl fused gamma-carbolines. The process of the present invention is a more efficient process for preparing enantiomerically pure substituted heterocycle fused gamma-carbolines. The compounds of the present invention are useful as 5-HT2 receptor agonists and antagonists used in treating disorders of the central nervous system. |