abstract |
Enzymes (3R) -hydroxyacyl-ACP dehydratases involved in the biosynthesis of mycolic acids and their use for the screening of antibiotics, drugs which may be used to treat infections in humans or animals due to Corynebacterineae and more particularly infections due to pathogenic mycobacteria (Mycobacterium tuberculosis, M. africanum, M. leprae, M. ulcerans, M. microti, M. bovis, M. abscissus, M. avium, M. fortuitum, M. kansasii. ..) as well as infections caused by other genera such as Nocardia, Rhodococcus, Gordona ... |