| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_930d07fdce921bf82f9485788574a96f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90241 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate |
2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b48421adb087cc439dc5faec29ba9384
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c13de870e3bec0a73579615a9c4ce02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bc4b8488c48986aff4730998953abd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e40e2f35855d0bb7581fc372fcc78ab0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ec4c3b3fbc05de133f132249dd2adb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1fbf65caa2aae42249e2608f772aaf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03beb453d380e692bd897ff6fb0aa74f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb426f830a4181c46045f86a06add761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab64737e0fd4c0b881cd6778785625b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36863315ba2e2e01625e65c69555c868 |
| publicationDate |
2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2672380-A1 |
| titleOfInvention |
Yeast platform construction and screening methods |
| abstract |
The present invention relates to a cell which is suitable for screening a candidate agent as being an inhibitor of the metabolism of tryptophan to NAD+ and/or a modulator of NAD+ levels, which cell comprises functional genes of a pathway enabling the metabolism of tryptophan to NAD+ and wherein the cell includes a copy of an exogenous gene of said pathway, from the same or different species as the cell, which exogenous gene is under the control of an inducible or constitutive promoter and wherein any endogenous copy of the gene having the same function as the exogenous gene is a non functioning gene. The present invention also relates to populations of such cells and to methods of screening candidate agents with such cells. |
| priorityDate |
2006-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |